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中文核心期刊

Volume 48 Issue 5
Sep.  2023
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LIU Chuang, LIU Li, ZHU Qiaomiao, LI Yanhao. Real-time monitoring of acoustic cavitation in high intensity focused ultrasound based on phase characteristics of transducer electrical signals[J]. ACTA ACUSTICA, 2023, 48(5): 1004-1011. DOI: 10.12395/0371-0025.2022113
Citation: LIU Chuang, LIU Li, ZHU Qiaomiao, LI Yanhao. Real-time monitoring of acoustic cavitation in high intensity focused ultrasound based on phase characteristics of transducer electrical signals[J]. ACTA ACUSTICA, 2023, 48(5): 1004-1011. DOI: 10.12395/0371-0025.2022113
shu

Real-time monitoring of acoustic cavitation in high intensity focused ultrasound based on phase characteristics of transducer electrical signals

  • 1.

    State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University　Chongqing　400016

  • 2.

    National Engineering Research Center of Ultrasonic Medicine　Chongqing　401121

More Information
  • PACS: 
    • 43.38  (Transduction, acoustical devices for the generation and reproduction of sound)
    • 43.80  (Bioacoustics)
    • 43.35  (Ultrasonics, quantum acoustics, and physical effects of sound)
  • Received Date: October 27, 2022
  • Revised Date: January 01, 2023
  • Available Online: September 11, 2023
    Graphical Abstract
    • Abstract

  • Acoustic cavitation induced by high intensity focused ultrasound (HIFU) can accelerate the thermal ablation of the target tissue. However, real-time monitoring of acoustic cavitation caused by HIFU is an urgent problem to be solved. The phase characteristics of the electrical signal of the HIFU transducer are established to analyze the real-time monitoring of acoustic cavitation. Under different HIFU excitation voltages, experimental research about real-time monitoring of acoustic cavitation in isolated bovine heart tissue irradiated by HIFU has been carried out. In addition, the phase difference of driving electrical signal is compared with the grayscale change of the B-ultrasound image and change results of subharmonic and broadband noise detected by broadband hydrophone. The research results show that when acoustic cavitation occurs, the change of phase difference of driving electrical signal has good consistency with the change of subharmonic and broadband noise detected by hydrophone. By the change of phase difference, real-time and accurate monitoring of the duration of acoustic cavitation occurring in target tissue irradiated by HIFU can be achieved, which provides a promising solution for real-time monitoring of acoustic cavitation caused by HIFU.

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    • References (22)
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