Abstract:
QA method and ln(D)U methods based on simultaneous measurements of Velocity(U)and arterial Diameter(D)using ultrasound technique are hotspots in the research of local Pulse Wave Velocity(PWV)detection.In present study,we do a comparative study on the accurate performance of QA and ln(D)U methods by the simulation and clinical trial systematically.According to the clinical measurements of carotid arterial wall displacement and central blood flow velocity during a cardiac cycle,an ultrasonic simulation model with preset theoretical value of PWV is established using Field Ⅱ platform.The results based on 30 simulations show that the normalized root-mean-square-errors of estimated PWVs based on QA and ln(D)U methods are 0.30±0.08 and 0.45±0.13,respectively.Moreover,the results based on 20 human subjects show that the estimated PWVs using QA and ln(D)U are correlated with the coefficient of 0.94;the Coefficient of Variations(CV)are 12.08%and 13.17%,respectively.The simulation and clinical results verify that the QA method is more accurate to estimate local pulse wave velocities.