Abstract: The research aims at validating the ability of topological imaging to blind holes in isotropic plates using Lamb waves. Due to the defect is not symmetric around the mid-plane of the plate, the effect of Lamb mode conversion will have to be taken into account. The imaging method is based on two computations of ultrasonic fields, one forward and one adjoint, performed for the defect-free reference medium. The exciting signal and scattered Lamb signals, which is caused by the blind hole, are used as emitting source to compute the forward problem and the adjoint problem respectively. With the help of the finite element simulations, the natural refocusing process of the multimode Lamb waves at the defect location is visually demonstrated by the snapshots at the different moments to strengthen the physical mechanism of the topological imaging method. The numerical results demonstrate that topological imaging has relatively stronger applicability to the blind hole in contrast to classical delay and sum method and time reversal method. The topological imaging could handle complex Lamb wave signals containing mode conversions without the imaging quality being affected. The proposed imaging method presents a certain developing potential for detecting and imaging asymmetric defects in plate-like configurations using Lamb waves.