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激光协同聚焦超声辐照生物样品增强热效应的实验和理论研究

赵瑾瑜, 陶超, 张淑仪, 范理, 水修基

赵瑾瑜, 陶超, 张淑仪, 范理, 水修基. 激光协同聚焦超声辐照生物样品增强热效应的实验和理论研究[J]. 声学学报, 2018, 43(4): 665-672. DOI: 10.15949/j.cnki.0371-0025.2018.04.026
引用本文: 赵瑾瑜, 陶超, 张淑仪, 范理, 水修基. 激光协同聚焦超声辐照生物样品增强热效应的实验和理论研究[J]. 声学学报, 2018, 43(4): 665-672. DOI: 10.15949/j.cnki.0371-0025.2018.04.026
ZHAO Jinyu, TAO Chao, ZHANG Shuyi, FAN Li, SHUI Xiuji. Experimental and theoretical studies for laser-enhanced thermal effects during focused ultrasound radiation on biological tissues[J]. ACTA ACUSTICA, 2018, 43(4): 665-672. DOI: 10.15949/j.cnki.0371-0025.2018.04.026
Citation: ZHAO Jinyu, TAO Chao, ZHANG Shuyi, FAN Li, SHUI Xiuji. Experimental and theoretical studies for laser-enhanced thermal effects during focused ultrasound radiation on biological tissues[J]. ACTA ACUSTICA, 2018, 43(4): 665-672. DOI: 10.15949/j.cnki.0371-0025.2018.04.026

激光协同聚焦超声辐照生物样品增强热效应的实验和理论研究

基金项目: 

国家自然科学基金项目(11304160)

公益性行业科研专项(201510068)资助

详细信息
    通讯作者:

    张淑仪,zhangsy@nju.edu.cn

  • PACS: 
      43.35;43.25;42.62

Experimental and theoretical studies for laser-enhanced thermal effects during focused ultrasound radiation on biological tissues

  • 摘要: 对中等强度聚焦超声在生物样品中产生的热效应以及激光协同超声增强热效应进行了实验和理论研究。实验上,对生物和仿生样品在超声作用和激光协同超声作用下加热情况进行测量,通过对比表明,激光协同超声作用于生物样品,引起空化效应以及温度升高更为明显。同时,理论上对聚焦超声在生物样品中衰减产生的热效应、超声空化以及激光协同超声增强空化及其产生热效应进行机理分析。通过对机理的分析表明,激光引起的光致核化使超声空化更易于产生,有效的增强空化效应,进而增强热效应。为对具体实验给出量化分析和估算,通过理论与实验结果相拟合,对超声传播引起的温度升高进行计算,并估算超声和激光协同超声产生空化微泡对加热效应的不同贡献,为空化效应在超声治疗中的贡献提供参考数据。
    Abstract: The thermal effects induced by a moderate intensity focused ultrasound and enhanced by combined laser pulses for bio-tissues and tissue-phantom are studied experimentally and theoretically. At first, the heating effects of bio-tissues and tissue-phantom induced by ultrasound and enhanced by laser are measured experimentally. The heating processes induced by attenuations of focused ultrasonic waves and cavitation effects of the focused ultrasound and combined laser are analyzed theoretically. By analyzing the mechanisms of these effects, it is indicated that the laser nucleation makes the cavitation bubble generation more easily, which can effectively enhance the ultrasonic cavitation effects, and then enhance the thermal effects for the samples. On the other hand, to evaluate quantitatively the heating processes induced by the the experimental results focused ultrasound and enhanced by the pulsed laser, by fitting the theoretical calculations to the corresponding cavitation bubbles and rising temperatures induced by the focused ultrasound with and without laser can be estimated approximately
  • 期刊类型引用(2)

    1. 田淑爱,丁婷,田志鑫,杨录. 结合空化微泡母小波变换的高空化噪声比超快速主动空化成像方法. 应用声学. 2020(06): 849-856 . 百度学术
    2. 李龙,谭华勇,周孟戈. 基于激光聚焦超声增强的聚焦超声特性研究. 应用激光. 2019(04): 690-695 . 百度学术

    其他类型引用(2)

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  • 被引次数: 4
出版历程
  • 收稿日期:  2017-01-05
  • 修回日期:  2017-06-26
  • 网络出版日期:  2022-06-27
  • 刊出日期:  2022-06-27

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