Abstract: In problem of Adaptive Self-Noise Canceling in flank array sonar,reference signals'pick up and fusion withhigh quality are the key points.First the distribution characteristic of self-noise along the concerned frequency band isdiscussed,then the conception of ANC addressing Harmonic Line interference Cluster is Proposed.Following reference1,where a theoretical solution of ANC addressing single frequency line interference is given,this paper will discuss the case of Multi-Tone Line interference.Based on the notch filtering quality faCtor,the design ofLine interference canceller with constant Q is approached.An effective scheme to synthesize the Harmonic Line Clusteris also proposed in addition.Relative computer simulation and sea trial have been carried out,with satisfying results.